Organic Acid Test OAT / Organic Acid Test
The Organic Acid Test (OAT) offers a comprehensive metabolic analysis of a patient's overall health with 76 markers. Provides an accurate assessment of intestinal yeast and bacteria.
Nuevas Adiciones al GI-MAP Mejoran la Visión de la Salud del Paciente ¡Actualización de Agosto 2023!
El Péptido de Gluten Fecal evalúa cuantitativamente el péptido inmunogénico del gluten en las heces después de una ingesta reciente (dentro de dos a cuatro días). Los resultados pueden guiar a los profesionales a la fuente de exposiciones al gluten "ocultas", permitiendo una mayor adherencia a una dieta terapéutica adecuada.
El marcador Péptido de Gluten (Gluten en Heces) está disponible como una adición opcional al GI-MAP o como una prueba independiente.
Fecal Gluten Peptide (Stool Gluten)
Abnormally high levels of these microorganisms can cause or worsen behavioral disorders, hyperactivity, movement disorders, fatigue, and immune function.
Many people with chronic diseases and neurological disorders often excrete various abnormal organic acids in their urine. The cause of these high levels could include the use of oral antibiotics, high-sugar diets, immune deficiencies, acquired infections, and genetic factors.
The organic acid test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only organic acid test that includes markers for oxalates, which are highly correlated with many chronic diseases.
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The information of test helpsprioritize treatment intervention decisions, along with symptoms and medical history, between candida (fungus) and clostridia (bacteria).
- Treating candida only when HPHPA and 4-cresol toxins from the clostridial bacteria are present can cause significant problems that aggravate the digestive system, but also lead to adverse changes in neurochemicals that affect behaviors, cognitive abilities, mood and mental stability.
- The proofevaluates high oxalate content(also known as oxalic acid). Oxalate is a compound found in many foods such as nuts (for example, almonds), fruits (for example, berries), and certain vegetables (for example, spinach).
- Oxalate can also be produced by the overgrowth of candida, aspergillus mold, as well as certain metabolic imbalances related to deficiency of oxalate-metabolizing enzymes. High oxalate is often associated with joint and muscle pain, but can also lead to bladder and bowel discomfort.
- Severe cases of oxalate buildup can cause kidney stones. Oxalate can trap heavy metals like mercury, lead, and arsenic in the body and cause mineral imbalances.
Cat Simmons, MS, RD, CDCES Autora: Cat Simmons, MS, RDN, CDCES
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Shan, L., et al., Structural basis for gluten intolerance in celiac sprue. Science, 2002. 297(5590): p. 2275-9.
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Moreno, M.L., et al., Biomarkers to Monitor Gluten-Free Diet Compliance in Celiac Patients. Nutrients, 2017. 9(1).
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Pietzak, M.M., Follow-up of patients with celiac disease: achieving compliance with treatment. Gastroenterology, 2005. 128(4 Suppl 1): p. S135-41.
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Lerner, B.A., et al., Detection of Gluten in Gluten-Free Labeled Restaurant Food: Analysis of Crowd-Sourced Data. Am J Gastroenterol, 2019. 114(5): p. 792-797.
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Comino, I., et al., Monitoring of gluten-free diet compliance in celiac patients by assessment of gliadin 33-mer equivalent epitopes in feces. Am J Clin Nutr, 2012. 95(3): p. 670-7.
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.
Q.1500
- The test evaluates specific toxins related to variousclostridial bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health. For example, certain strains of C. diff. they produce virulence factors that cause inflammation, bleeding, and diarrhea within the digestive system. However, there are other clostridial toxins that act outside of the digestive system.
- The main toxins evaluated in the test linked to different strains of clostridia are HPHPA and 4-cresol. Both HPHPA and 4-cresol can inhibit a dopamine converting enzyme that leads to excess dopamine in the brain and nervous system.
- High dopamine can form toxic compounds that negatively affect brain cells. Prolonged elevation of these dopamine-related compounds such as DOPAC (and dopamine-o-quinone, a compound not measured in the test) is known to trigger free radical damage within the brain.
- Elevation of the neurotransmitter dopamine can also cause mood instability and other cognitive problems. In severe cases, the presence of these clostridial toxins can trigger aggressive and self-injurious behavior due to high amounts of dopamine. This is a common scenario in people with special needs, such as people with autism. Screening for clostridia organic acid toxins is essential for anyone struggling with a developmental disorder, mental health issues, and neurological disease.